Accelerating the Discovery of New Antimicrobial Compounds
Thursday, April 26, 2018
8AM PDT | 11AM EDT | 4PM BST | 5PM CEST
The increasing occurrence of multidrug resistant (MDR) bacteria is driving an urgent demand for the discovery of new antibiotics. The incidence of MDR bacteria is becoming a serious problem, especially in the hospital setting. High-throughput screening methodologies are important to speed up the discovery of new antibiotics. Automation and miniaturization are important components in this process, since they significantly decrease the amount of drugs and reagents needed.
During this webcast we will present some of the main assays used in the early stages of the antimicrobial compound discovery:
- Minimal Inhibitory Concentration (MIC) assay,
- synergy assay among 2 or 3 antimicrobial compounds,
- determination of the concentration of bacteria in liquid cultures,
- cytotoxicity assay
- bacterial growth/killing curves.
This webcast has been produced on behalf of the sponsor who retains sole responsibility for content. About this content.