Using mass cytometry to identify clinically relevant biological signatures in human health and disease
Tuesday May 4, 2021 at 8am PDT, 11am EDT, 5pm CEST
Mass cytometry has emerged in recent years as a powerful tool for single-cell analysis in both basic and clinical research studies.
This virtual seminar features two speakers discussing mass cytometry technology and its application in human immunology and disease research. The virtual seminar’s featured speaker is Dr. Brice Gaudilliere of the Stanford School of Medicine. Gaudilliere has over 15 years of experience in cell signaling biology, immunology and translational application of next-generation single-cell technologies. Research in the Gaudilliere Lab combines high-parameter mass cytometry (suspension and Imaging Mass Cytometry™) with other proteomics approaches to study how the human immune system responds and adapts to physiological or pathological stressors. In this virtual seminar you will learn how the Gaudilliere group is applying mass cytometry and other proteomic technologies to obtain multi-omic views of several clinical scenarios, including:
- immune mechanisms of surgical recovery and complications;
- pregnancy and preterm birth;
- immune dysfunction and outcomes prediction in patients with COVID-19.
Michelle Poulin, Manager of North American Field Applications at Fluidigm, will do a brief introduction of mass cytometry including a technical description of the core technology, cytometry by time-of-flight (CyTOF®). She’ll also provide an overview of the isotopic metal-labeled antibodies and panel kits that enable analysis of over 50 markers per cell.
and (by courtesy) of Pediatrics Stanford University School of Medicine