Harnessing Metabolic Reprogramming for Translational Therapy in Cancer

Originally Aired May 6, 2019

Synthetic biology technologies have ushered in remarkable advances in cellular engineering, growing our arsenal of tools for cancer treatment. Increasingly, the metabolic pathways of cells have emerged as attractive targets for rewiring cell behavior, enhancing the efficacy of such treatments as T cell-receptor (TCR)-and chimeric antigen receptor (CAR)-based immunotherapies. In this Cell Press Webinar, Shikhar Mehrotra (Medical University of South Carolina), Greg Delgoffe (University of Pittsburgh), and Jeff Rathmell (Vanderbilt University Medical Center) will explore the interplay between cancer and immunometabolism with an eye to recent innovations in the therapeutic landscape.

Jeff Rathmell
Professor of Pathology, Microbiology, and Immunology Professor of Cancer Biology
Director, Vanderbilt Center for Immunobiology Vanderbilt University Medical Center
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Shikhar Mehrotra
Associate Scientific Director- Center of Cellular Therapy
Department of Surgery, Microbiology & Immunology
Medical University of South Carolina
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Greg Delgoffe
Assistant Professor
Tumor Microenvironment Center
Department of Immunology
University of Pittsburgh
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Moderator: Simona Fiorani
Lead Editor

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