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Using single-cell profiling to investigate lung immune responses in mild and critical COVID-19 patients

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The synchronization of innate and adaptive lung immune responses to SARS-CoV-2 during COVID-19 pneumonitis is poorly understood. In this webcast, the speaker will describe applying single-cell profiling to bronchoalveolar lavages from patients with mild or critical COVID-19 versus non-COVID-19 pneumonia as a control, and how this research is furthering understanding of lung-localised immunity and the inflammation landscape during COVID-19.

Learn about:

  • How single-cell immune profiling techniques has been used to investigate innate and adaptive immune responses to COVID-19
  • Distinguishing cellular, molecular, and inflammatory features of mild and severe COVID-19
  • How local immune populations and other cell types coordinate to facilitate successful lung tissue repair or contribute to the pathophysiology of COVID-19–associated fibrosis and pneumonitis
This webcast has been produced for 10x Genomics by Nature Research Custom Media. The sponsor retains sole responsibility for content. About this content.


Dr. Diether Lambrechts
Full Professor of Medicine, Dept. of Human Genetics Science Director and Group Leader, Center for Cancer Biology (CCB)
KU Leuven
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Moderator: Sarah Hiddleston
Science Journalist
Nature Research for Nature Middle East
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