Human Cell Atlas: A spatially resolved map of human breast tissue

Tuesday, March 30, 2021
9AM PDT | 12PM EDT | 5PM BST | 6PM CEST

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Human Cell Atlas: A spatially resolved map of human breast tissue

Tuesday, March 30, 2021
9AM PDT | 12PM EDT | 5PM BST | 6PM CEST

Overview

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The mission of the Human Cell Atlas is to create comprehensive reference maps of all human cells to describe and define the cellular basis of health and disease. Single-cell analysis methods allow us to catalogue the vast diversity of cellular phenotypes that exist in a sample. However, cell behaviour is also a function of all that surrounds it, and how cells organize and interact within a tissue sample can impact biological and clinical outcomes.

With the advent of high-resolution imaging platforms like CODEX®, researchers can now analyse the spatial and geographical context of each individual cell and build comprehensive maps of all human cells and tissues. In the true sense of the word, we can now build a complete ‘cell atlas.’

In this webcast, Dr. Kai Kessenbrock will explain how spatial phenotyping can enhance the biological insights from Human Cell Atlas initiatives. Using the Human Breast Cell Atlas project as an example, Dr. Kessenbrock will explain how his team discovered unique cellular niches within the breast tissue microenvironment and how their spatial proximity gives us a more comprehensive view of the biology underlying each sample.

You will learn:

  • How spatial phenotyping can generate high resolution maps of millions of cells in a tissue section
  • How to complement single-cell RNA-Seq data with CODEX® spatial proteomic data
  • How to use spatial analysis tools to study cellular niches and neighborhoods within tissue samples
This webcast has been produced by Akoya Biosciences, who retains sole responsibility for content. About this content.

Presenters

Presenter
Dr. Kai Kessenbrock
Assistant Professor, Biological Chemistry
Chao Family Comprehensive Cancer Center,
University of California, Irvine
View Biography
Presenter
Moderator: Sarah Hiddleston
Science Journalist
Nature Research for Nature Middle East
View Biography